Neonatal Ataxia in Coton de Tuléar

Neonatal Ataxia leads to a degeneration of the nervous system. About 10% of Coton de Tulear carry the genetic mutation responsible for this disease. A reliable DNA test can be used to detect breeders, to adapt mating to avoid breeding puppies and to spread the disease in the breed.

A serious inherited disease

Neonatal Ataxia leads to degeneration of the nervous system. The first symptoms are manifested from birth by disturbances of balance and the inability of the puppy to coordinate its movements. Puppies unable to stand or move should be euthanized

A fairly common disease

About 10% of European Coton de Tuléar carries the genetic mutation responsible for Neonatal Ataxia. A breeder can unknowingly mate a male carrier and a female carrier and breed litter with infected puppies.
A breeding dog that is a healthy carrier does not develop the disease but transmits it to 50% of its offspring. A mutation-bred stallion, which reproduces a lot, then spreads the disease within the breed and helps to increase the frequency of the mutation and increase the number of pups reached.

A preventable disease

When that a dog is affected by the disease, it means that both parents are at least healthy carriers (they can also be reached without symptoms still visible). Breeders who are not sensitized to Neonatal Ataxia can unknowingly mate with the breeders carrying the mutation and give birth to infected puppies.
A DNA test, called the BNAT test (for Bandera's Neonatal Ataxia), is used to detect Ataxia. Neonatal Coton de Tuléar with a reliability greater than 99%

Avoid giving birth to puppies

The breeder to secure his breeding and not to take the risk of making puppies infected, must absolutely detect his using the DNA test.
When acquiring a puppy for breeding or when using a stallion for breeding, the breeder verifies the dog's genetic status for breeding. Neonatal ataxia by asking for the result of the DNA test

A DNA test easy to carry out

The veterinarian carries out a simple oral swab that is sent to the laboratory. The result, delivered in a few days, indicates if the tested dog is healthy, healthy carrier or affected by Neonatal Ataxia. The result in the form of a genetic certificate must be used as a guarantee in the context of a breeding or to justify the sale of puppies free of Neonatal Ataxia.
The veterinarian who prematurely observes neurological problems in a Coton de Tulear puppy can implement the DNA test to confirm or invalidate the diagnosis of Neonatal Ataxia. If the puppy is actually reached, the parents must also be tested.
Breeders who know the genetic status of their dogs can select their breeders, adapt mating, avoid causing puppies and limit the spread of this dog. severe neurological disease in the breed.
Dr Guillaume QUENEY
Laboratory ANTAGENE

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