Chemical castration in dogs
A male dog may be temporarily castrated, chemically , without going through the surgery box. There are different molecules and different routes of administration of these chemicals whose effect and duration will be variable.
A dog can be chemically castrated by injecting progestagens: this hormone will inhibit the secretions stimulating the pituitary hypothalamic axis and, consequently, the secretion of testosterone by its anti-androgenic effect. The effect of the injection varies from one individual to another, but as a general rule, it manifests itself after a few days and is maintained for a few months (between 1 and 6 months).
The implant contraceptive: how does it work?
In recent years is marketed a contraceptive implant .
This is a "matrix" that the veterinarian will "inject" subcutaneously into simple consultation and that will release gradually and continuously hormones.
The implant gradually releases Deslorelin, which will inhibit the secretion of FSH and LH in the pituitary gland by blocking the activity of endogenous GnRH on its pituitary receptor. At the end of a cascade, testosterone will eventually be more secreted. And the dog will be rendered temporarily sterile, after a minimum of 6 weeks (or 8 to 12 weeks depending on the presentation) for a first implantation, and this for 6 to 12 months (and sometimes up to 18 months or more) . If you wish to continue the effect beyond that, you will have to have another implant implanted by your veterinarian, and so on.
The advantage of these chemical castration methods lies essentially in the fact that their effects are reversible. A dog will be able to reproduce once again the effects dissipated. These methods may also be used for the prevention of prostatic diseases (such as benign hyperplasia, for example).
Few side effects
Implant acting upstream of the pituitary, it is quite appropriate before performing surgical castration for a behavioral purpose, to ensure that sterilization will have conclusive effects. In addition, the implant has the advantage of having few side effects, apart from potentially an effect called "flare up" (excessive excitation) during the first 2 to 3 weeks. This effect is not at all routine, and the excitement disappears completely after 2-3 weeks.
Progestagen injections have the advantage of having a shorter effect, but the risk of side effects is more important (polyphagia, diabetes, mammary tumor in the male, no return of spermatogenesis, etc.)
Also to read: surgical castration of the dog
Doctor Laurence De Meester - de Courcy, Veterinarian
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